Partly owned by Hollywood actor John Malkovich, this is Lisbon’s hippest club and one of Europe’s most fashionable (especially when it comes to the interior decoration), having attracted visiting stars like Cameron Diaz and Prince. It couldn’t be a more stylish place, with a spacious interior decorated with funky and retro furniture. Top DJs spin cutting-edge music downstairs in a frenzied dance floor, while the top floor has a more relaxed vibe with an alternative soundtrack. A balcony running around the building overlooks the river, while a breezy rooftop terrace is a great place to watch the sun rise early in the morning. As expected, everyone tries to come here, so expect highly selective doormen and long queues on weekends. This is THE place to spend the night in Lisbon.